Format

Send to

Choose Destination
Ital J Pediatr. 2018 Mar 14;44(1):36. doi: 10.1186/s13052-018-0474-0.

Vitamin K deficiency: a case report and review of current guidelines.

Author information

1
Pediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy. mrosaria.marchili@opbg.net.
2
Pediatric Department, University of Tor Vergata, Rome, Italy.
3
Pediatric and Infectious Disease Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, Rome, Italy.

Abstract

BACKGROUND:

Vitamin K, a fat soluble vitamin, is a necessary cofactor for the activation of coagulation factors II, VII, IX, X, and protein C and S. In neonatal period, vitamin K deficiency may lead to Vitamin K Deficiency Bleeding (VKDB).

CASE PRESENTATION:

We present the case of a 2 months and 20 days Caucasian male, presented for bleeding from the injections sites of vaccines. At birth oral vitamin K prophylaxis was administered. Neonatal period was normal. He was exclusively breastfed and received a daily oral supplementation with 25 μg of vitamin K. A late onset vitamin K deficiency bleeding was suspected. Intravenous Vitamin K was administered with complete recovery.

CONCLUSIONS:

Nevertheless the oral prophylaxis, our case developed a VKDB: it is necessary to revise the current guidelines in order to standardize timing and dosage in different clinical conditions.

KEYWORDS:

Bleeding; Breastfeeding; Case report; Deficiency; Vitamin K

PMID:
29540231
PMCID:
PMC5853086
DOI:
10.1186/s13052-018-0474-0
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center