Send to

Choose Destination
Cold Spring Harb Perspect Med. 2018 Nov 1;8(11). pii: a032144. doi: 10.1101/cshperspect.a032144.

Transmission and Epidemiology of Hepatitis E Virus Genotype 3 and 4 Infections.

Author information

Royal Cornwall Hospital, Truro TR1 3LJ, United Kingdom.
European Centre for Environment and Human Health, University of Exeter, Truro TR1 3LJ, United Kingdom.
Department of Virology, Hepatitis E Virus National Reference Centre, Toulouse University Hospital, 31059 Toulouse, France.
Toulouse-Purpan Centre for Pathophysiology, INSERM UMR1043/CNRS UMR 5282, CPTP, Toulouse University Paul Sabatier, 31024 Toulouse, France.


Following the introduction of robust serological and molecular tools, our understanding of the epidemiology of zoonotic hepatitis E virus (HEV) has improved considerably in recent years. Current thinking suggests that consumption of pork meat products is the key route of infection in humans, but it is certainly not the only one. Other routes of infection include environmental spread, contaminated water, and via the human blood supply. The epidemiology of HEV genotype (gt)3 and gt4 is complex, as there are several sources and routes of infection, and it is likely that these vary between and within countries and over time.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center