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J Ultrasound Med. 2018 Nov;37(11):2689-2698. doi: 10.1002/jum.14602. Epub 2018 Mar 12.

Comparison of the Diagnostic Performance of Power Doppler Ultrasound and a New Microvascular Doppler Ultrasound Technique (AngioPLUS) for Differentiating Benign and Malignant Breast Masses.

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Department of Radiology, CHA Bundang Medical Center, CHA University, Seoul, Korea.


This study was performed to compare the diagnostic performance of power Doppler ultrasound (US) and a new microvascular Doppler US technique (AngioPLUS; SuperSonic Imagine, Aix-en-Provence, France) for differentiating benign and malignant breast masses. Power Doppler US and AngioPLUS findings were available in 124 breast masses with confirmed pathologic results (benign, 80 [64.5%]; malignant, 44 [35.5%]). The diagnostic performance of each tool was calculated to distinguish benign from malignant masses using a receiver operating characteristic curve analysis and compared. The area under the curve showed that AngioPLUS was superior to power Doppler US in differentiating benign from malignant breast masses, but the difference was not statistically significant.


AngioPLUS; Doppler (techniques/physics); Doppler imaging; breast (diagnostic); breast masses; ultrasound; vascular


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