Format

Send to

Choose Destination
Appetite. 2018 Jun 1;125:492-501. doi: 10.1016/j.appet.2018.03.006. Epub 2018 Mar 7.

Eating less or more - Mindset induced changes in neural correlates of pre-meal planning.

Author information

1
Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany.
2
Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany; Institute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
3
German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.
4
Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany; Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
5
National Institute for Health Research Bristol, Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, BS8 1TU, United Kingdom.
6
Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, 72076 Tübingen, Germany; German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany; Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Interfaculty Centre for Pharmacogenomics and Pharma Research, Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany. Electronic address: hubert.preissl@uni-tuebingen.de.

Abstract

Obesity develops due to an imbalance between energy intake and expenditure. Besides the decision about what to eat, daily energy intake might be even more dependent on the decision about the portion size to be consumed. For decisions between different foods, attentional focus is considered to play a key role in the choice selection. In the current study, we investigated the attentional modulation of portion size selection during pre-meal planning. We designed a functional magnetic resonance task in which healthy participants were directed to adopt different mindsets while selecting their portion size for lunch. Compared with a free choice condition, participants reduced their portion sizes when considering eating for health or pleasure, which was accompanied by increased activity in left prefrontal cortex and left orbitofrontal cortex, respectively. When planning to be full until dinner, participants selected larger portion sizes and showed a trend for increased activity in left insula. These results provide first evidence that also the cognitive process of pre-meal planning is influenced by the attentional focus at the time of choice, which could provide an opportunity for influencing the control of meal size selection by mindset manipulation.

KEYWORDS:

Dorsolateral prefrontal cortex; Food; Insula; Mindset; Orbitofrontal cortex; fMRI

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center