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Cleve Clin J Med. 2018 Mar;85(3):231-239. doi: 10.3949/ccjm.85a.17019.

Acute cardiorenal syndrome: Mechanisms and clinical implications.

Author information

1
Department of Internal Medicine, Western Michigan University School of Medicine, Kalamazoo, MI, USA. guramrinder.thind@med.wmich.edu.
2
Chair and Associate Program Director, Department of Internal Medicine, Kalamazoo, MI, USA.
3
Associate Professor of Medicine, Western Michigan University School of Medicine, Kalamazoo, MI, USA.
4
Director, Medical Critical Care Services, Borgess Medical Center, Kalamazoo MI, USA.
5
Associate Professor of Medicine and Director, Pulmonary and Critical Care Curriculum, Western Michigan University School of Medicine, Kalamazoo, MI, USA.

Abstract

Cardiac and renal dysfunction often coexist, and one begets the other. The association is referred to as cardiorenal syndrome. One subtype, acute cardiorenal syndrome, is often described as a clinical scenario in which acute worsening of cardiac function leads to acute kidney injury. Though this definition covers the basic pathophysiologic framework, a robust clinical definition is still lacking. Acute cardiorenal syndrome is common and often leads to emergency room visits and hospitalization. Our understanding of the hemodynamic mechanisms of acute cardiorenal syndrome is advancing. Correction of hypervolemia is the mainstay of therapy.

PMID:
29522391
DOI:
10.3949/ccjm.85a.17019
[Indexed for MEDLINE]
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