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Am J Epidemiol. 2018 Jun 1;187(6):1149-1152. doi: 10.1093/aje/kwy036.

Diesel Exhaust and Lung Cancer-Aftermath of Becoming an IARC Group 1 Carcinogen.

Author information

1
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Abstract

The International Agency for Research on Cancer reclassified diesel exhaust from Group 2A (probably carcinogenic to humans) to Group 1 (carcinogenic to humans) in 2012. Since then, reevaluation and reanalysis of 2 major studies (Diesel Exhaust in Miners Study and Trucking Industry Particle Study) that were influential to the International Agency for Research on Cancer evaluation have replicated the original findings and demonstrated the suitability of these epidemiologic data for the quantitative risk assessment needed to set safe exposure limits in occupational and outdoor ambient environments. The challenge now is to protect the workers and general populations in urban areas from the carcinogenicity of diesel exhaust.

PMID:
29522191
PMCID:
PMC5982841
[Available on 2019-06-01]
DOI:
10.1093/aje/kwy036

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