Format

Send to

Choose Destination
Plant Signal Behav. 2018 Mar 4;13(3):e1449544. doi: 10.1080/15592324.2018.1449544. Epub 2018 Mar 26.

Aldehyde dehydrogenases and the hypothesis of a glycolaldehyde shunt pathway of photorespiration.

Author information

1
a Department of Microbiology and Plant Pathology , University of California Riverside , Riverside CA , USA.
2
b Department of Pharmaceutical and Biomedical Sciences , College of Pharmacy, California Northstate University , Elk Grove , CA , USA.

Abstract

Aldehyde dehydrogenase enzymes (ALDHs) catalyse the oxidation of a broad range of aliphatic and aromatic aldehydes to their corresponding carboxylic acids using NAD+ or NADP+ as cofactors. In our article published in Scientific Reports, we demonstrated that mutations in Arabidopsis ALDH3I1 and ALDH7B4 genes altered the cellular contents of NAD(P)H, the total as well as the reduction state of glutathione; and decreased the efficiency of photosynthesis, thus placing ALDH activity as an important source of reducing power for cellular redox homeostasis. Our results also revealed that the ALDHs contribute to the reducing power required for the nitrate assimilation. Here, we discussed and elucidated the innovative hypothesis of the glycolaldehyde shunt pathway of photorespiration that would involve ALDHs generating in contrast to the known core photorespiration reactions, a net gain of two moles of NAD(P)H to support nitrate assimilation, glutathione homeostasis and ROS detoxification.

KEYWORDS:

Aldehyde dehydrogenase; NAD(P)H; glycolaldehyde; nitrate assimilation; photorespiration

PMID:
29521550
PMCID:
PMC5927671
[Available on 2019-03-26]
DOI:
10.1080/15592324.2018.1449544

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center