Format

Send to

Choose Destination
Appl Microbiol Biotechnol. 2018 Apr;102(8):3583-3594. doi: 10.1007/s00253-018-8890-z. Epub 2018 Mar 8.

Biotechnological production of mono- and diamines using bacteria: recent progress, applications, and perspectives.

Author information

1
Genetics of Prokaryotes, Faculty of Biology & CeBiTec, Bielefeld University, Universitätsstr. 25, 33615, Bielefeld, Germany. volker.wendisch@uni-bielefeld.de.
2
Genetics of Prokaryotes, Faculty of Biology & CeBiTec, Bielefeld University, Universitätsstr. 25, 33615, Bielefeld, Germany.

Abstract

Common plastics such as polyamides are derived typically from petroleum or natural gas. Fossil-based polyamide production often involves toxic precursors or intermediates. By contrast, bio-based polyamides offer a realistic alternative. Bio-based routes to monomeric precursors of polyamides such as diamines, dicarboxylic acids, and omega-amino acids have been developed. Recent advances in the metabolic engineering of the biotechnologically relevant Escherichia coli and Corynebacterium glutamicum for the production of monoalkylamines such as omega-amino acids as well as diamines are presented.

KEYWORDS:

Corynebacterium glutamicum; Diamine; Escherichia coli; Lactam; Metabolic engineering; Omega-amino acid

PMID:
29520601
DOI:
10.1007/s00253-018-8890-z
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center