Format

Send to

Choose Destination
Vet Microbiol. 2018 Mar;216:107-118. doi: 10.1016/j.vetmic.2018.01.015. Epub 2018 Feb 2.

First four Oral Rabies Vaccination campaigns of the red foxes in Greece: Evaluating factors and assessment.

Author information

1
Virology Laboratory-National Reference Laboratory for Rabies in Animals, Department of Molecular Diagnostics, FMD, Virological, Rickettsial & Exotic Diseases, Directorate of Veterinary Center of Athens, Directorate General of Veterinary Services, Ministry of Rural Development and Food, Athens, Greece. Electronic address: dppapatheodorou@minagric.gr.
2
Virology Laboratory-National Reference Laboratory for Rabies in Animals, Department of Molecular Diagnostics, FMD, Virological, Rickettsial & Exotic Diseases, Directorate of Veterinary Center of Athens, Directorate General of Veterinary Services, Ministry of Rural Development and Food, Athens, Greece.
3
Department of Zoonoses, Animal Health Directorate, Directorate General of Veterinary Services, Ministry of Rural Development and Food, Athens, Greece.
4
School of Science & Technology, Hellenic Open University, Patra, Greece.

Abstract

Following the last animal rabies outbreak in Greece in 2012, Oral Rabies Vaccination (ORV) campaigns of red foxes (Vulpes vulpes) were conducted in order to halt the spread of the disease, as widely and effectively have also been implemented in other countries. The present study aims to report the main outcomes following the first Greek ORV campaigns during autumn 2013, 2014, 2015 and spring 2016, to assess their effectiveness and to investigate factors potentially related to their success. Blood samples, mandible bones and teeth, derived by 452 foxes, were tested for rabies antibody titration, animal age determination and tetracycline (TTC) detection. The laboratory results obtained were statistically analyzed. High seroprevalence and TTC detection rates were obtained following the autumn campaigns studied, while these rates were significantly reduced following the spring campaign. The year or the season of the vaccination campaign, the estimated age group of the animal and the geographical Regional Unit (RU), where the animal was hunted, were identified as important factors. On the contrary, no significance could be ascertained for TTC detection based on exclusively previous uptake, use of filter paper, blood sample type and quality, as well as sex of animal. Based on the monitoring results achieved, the first ORV campaigns conducted in the country can be generally considered to be satisfactory. No positives cases were detected since May 2014. Seasonal, geographical parameters and factors related to fox ecology may interfere with monitoring results and should be always considered when planning future ORV programs.

KEYWORDS:

Assessment; Efficacy; Oral rabies vaccination; Red fox; Serological; Tetracycline

PMID:
29519504
DOI:
10.1016/j.vetmic.2018.01.015
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center