Format

Send to

Choose Destination
Retina. 2019 Jun;39(6):1091-1099. doi: 10.1097/IAE.0000000000002090.

LONGITUDINAL CHANGES IN CHOROIDAL AND RETINAL THICKNESSES IN CHILDREN WITH MYOPIC SHIFT.

Jin P1,2, Zou H1,2, Xu X1,2, Chang TC3, Zhu J1, Deng J2, Lv M1, Jin J1, Sun S4, Wang L5, He X1,5.

Author information

1
Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
2
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.
3
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida.
4
Jiading Center for Disease Prevention and Control, Shanghai, China.
5
Department of Maternal and Child Health, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.

Abstract

PURPOSE:

To elucidate the development of the choroid and retina in children, and to explore changes in these during myopic shift.

METHODS:

A total of 118 children aged 7 to 12 years participated in this 1-year longitudinal study. Children underwent several examinations at baseline and follow-up, including cycloplegic refraction, axial length measurement, and swept-source optical coherence tomography. Thickness changes in the choroid and retina were compared among children with or without myopic shift.

RESULTS:

Eighty-eight children (74.6%) developed a myopic shift after 1 year, and their central foveal choroid was significantly attenuated (P < 0.01). No significant change was observed in choroids of children without myopic shift (P = 0.83). Choroidal thickness decreased in all subfields during myopic shift, whereas the thickness of the retinal layers increased or were unchanged in most subfields. Axial length increase and central foveal choroidal thinning were associated with myopic shift (R = 0.157, P < 0.01), but axial length increase was not significantly related to choroidal thinning (P > 0.05).

CONCLUSION:

Choroidal thinning occurs early in myopic progression. Axial length increase and choroidal thinning are independently associated with myopic shift.

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center