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Bone Marrow Transplant. 2018 Aug;53(8):1030-1037. doi: 10.1038/s41409-018-0137-1. Epub 2018 Mar 7.

Variability of nutritional practices in peritransplant period after allogeneic hematopoietic stem cell transplantation: a survey by the Complications and Quality of Life Working Party of the EBMT.

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Department of Internal Medicine, School of Medicine, University of Zagreb, Zagreb, Croatia.
Hematology Unit, Oncology Department, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.
Hematology and Transplant Unit, Christie Hospital NHS Foundation Trust, Manchester, UK.
Department of Hematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
EBMT Data Office Leiden, Leiden, The Netherlands.
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
European Institute of Oncology, Milan, Italy.
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Clinical Research Institute, Helsinki University Hospital, Helsinki, Finland.


Recommendations on screening and nutritional support for patients undergoing hematopoietic stem cell transplantation (HSCT) have been presented by international nutritional societies, but nutritional practices remain poorly standardized. Following the general policy of the European Society for Blood and Marrow Transplantation (EBMT) to standardize transplantation procedures, the Complications and Quality of Life Working Party and Nursing Research Group carried out a survey among all EBMT centers about their current nutritional practices. The aim of this study was to better understand current practices, differences from available guidelines, and possible barriers for recommended nutritional therapy. Responses from 90 centers (19%) from 23 countries were received. We observed a marked variability in nutritional care between EBMT centers and a substantial lack of standardized operating procedures in screening patients for malnutrition and management of gastrointestinal GVHD. Furthermore, our study confirmed neutropenic diet as standard of care in most centers as well a preference for parenteral nutritional support over enteral. On the basis of these findings, future EBMT efforts will focus on better implementation of international nutritional guidelines into clinical practice.

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