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J Ultrasound Med. 2018 Oct;37(10):2433-2437. doi: 10.1002/jum.14585. Epub 2018 Mar 2.

The McConnell Sign is Seen in Patients With Acute Chest Syndrome.

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Departments of Emergency Medicine and Cardiology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.


Bedside ultrasound is often used as a part of the evaluation of patients who are critically ill. The McConnell sign is an important echocardiographic finding in some critically ill patients with pulmonary embolism and an acute right ventricular infarct. We present 3 critically ill patients with confirmed acute chest syndrome who showed the McConnell sign on echocardiography. In patients with sickle cell disease presenting with chest pain and shortness of breath, the presence of the McConnell sign does not narrow the differential diagnosis between pulmonary embolism, an acute right ventricular infarct, and acute chest syndrome.


McConnell sign; acute chest syndrome; critical care; echocardiography; emergency medicine; point-of-care ultrasound; pulmonary embolism


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