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Int J Mol Sci. 2018 Feb 28;19(3). pii: E686. doi: 10.3390/ijms19030686.

Potential Health Benefits of Olive Oil and Plant Polyphenols.

Author information

1
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. gorzynikdebicka@gmail.com.
2
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. p.e.przychodzen@gumed.edu.pl.
3
Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. francapp@hotmail.com.
4
Euro-Mediterranean Institute of Science and Technology (IEMEST), 90136 Palermo, Italy. francapp@hotmail.com.
5
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. alicjakuban@gumed.edu.pl.
6
Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. antonella.marino@hotmail.it.
7
Euro-Mediterranean Institute of Science and Technology (IEMEST), 90136 Palermo, Italy. antonella.marino@hotmail.it.
8
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. narcyz@gumed.edu.pl.
9
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. mwozniak@gumed.edu.pl.
10
Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. m.gorska@gumed.edu.pl.
11
Institute of Biomaterials and Biomolecular Systems, Department of Biophysics, University of Stuttgart, 70569 Stuttgart, Germany. m.gorska@gumed.edu.pl.

Abstract

Beneficial effects of natural plant polyphenols on the human body have been evaluated in a number of scientific research projects. Bioactive polyphenols are natural compounds of various chemical structures. Their sources are mostly fruits, vegetables, nuts and seeds, roots, bark, leaves of different plants, herbs, whole grain products, processed foods (dark chocolate), as well as tea, coffee, and red wine. Polyphenols are believed to reduce morbidity and/or slow down the development of cardiovascular and neurodegenerative diseases as well as cancer. Biological activity of polyphenols is strongly related to their antioxidant properties. They tend to reduce the pool of reactive oxygen species as well as to neutralize potentially carcinogenic metabolites. A broad spectrum of health-promoting properties of plant polyphenols comprises antioxidant, anti-inflammatory, anti-allergic, anti-atherogenic, anti-thrombotic, and anti-mutagenic effects. Scientific studies present the ability of polyphenols to modulate the human immune system by affecting the proliferation of white blood cells, and also the production of cytokines or other factors that participate in the immunological defense. The aim of the review is to focus on polyphenols of olive oil in context of their biological activities.

KEYWORDS:

Olea europea; anticancer therapy; hydroxytyrosol; oleuropein; olive oil; polyphenols

PMID:
29495598
PMCID:
PMC5877547
DOI:
10.3390/ijms19030686
[Indexed for MEDLINE]
Free PMC Article

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