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Impaired Bilirubin Conjugation.


StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019-.
2019 Mar 8.

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California Northstate University


Bilirubin circulates in both the conjugated and unconjugated forms (predominant). Disorders of impaired conjugation of bilirubin classically present with elevated levels of unconjugated or indirect bilirubin. [1][2]Major causes of impaired conjugation of bilirubin include inherited disorders and secondary causes such as drugs. [3][4]Disorders can range from an asymptomatic presentation to a very severe bilirubin encephalopathy (kernicterus). In this review, we focus on the inherited disorders and their management.

Copyright © 2019, StatPearls Publishing LLC.

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