Does a Dedicated Lumen for Parenteral Nutrition Administration Reduce the Risk of Catheter-Related Bloodstream Infections? A Systematic Literature Review

J Infus Nurs. 2018 Mar/Apr;41(2):122-130. doi: 10.1097/NAN.0000000000000270.

Abstract

Guidelines recommend using single-lumen central vascular access devices (CVADs) for the administration of parenteral nutrition (PN) or lipid-based solutions, or a dedicated lumen on a multilumen CVAD. Publications reviewed by the authors reported comparative rates of catheter-related bloodstream infection (CR-BSI) in patients with CVADs who received PN through a dedicated lumen compared with those who had PN administered through multilumen CVADs. Two studies included 650 patients with 1349 CVADs. CR-BSIs were equally distributed between the 2 groups. Both studies were poorly reported and had significant risk of bias. These results should be interpreted with caution.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Bacteremia
  • Catheter-Related Infections / prevention & control*
  • Central Venous Catheters / adverse effects*
  • Cross Infection / prevention & control
  • Humans
  • Parenteral Nutrition / instrumentation
  • Parenteral Nutrition / methods*
  • Risk Factors