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Sci Rep. 2018 Feb 26;8(1):3640. doi: 10.1038/s41598-018-21912-x.

Factors influencing intention to obtain the HPV vaccine in South East Asian and Western Pacific regions: A systematic review and meta-analysis.

Author information

1
School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.
2
Center of Pharmaceutical Outcomes Research (CPOR), Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
3
School of Pharmacy, University of Wisconsin, Madison, USA.
4
Asian Centre for Evidence Synthesis in Population, Implementation and Clinical Outcomes, (PICO), Health and Well-being Cluster, Global Asia in the 21st Century (GA21) Platform, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.
5
School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia. tahir.mehmood@monash.edu.
6
Asian Centre for Evidence Synthesis in Population, Implementation and Clinical Outcomes, (PICO), Health and Well-being Cluster, Global Asia in the 21st Century (GA21) Platform, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia. tahir.mehmood@monash.edu.
7
The Institute of Pharmaceutical Sciences (IPS), University of Veterinary & Animal Sciences (UVAS), Outfall road, Lahore, Pakistan. tahir.mehmood@monash.edu.

Abstract

Since licensing in 2006, there has been poor uptake of the HPV vaccine among the targeted population in the South East Asia Region (SEAR) and Western Pacific Region (WPR). A systematic review was conducted to identify the studies exploring the relationship between factors and intention for HPV vaccination among women in SEAR and WPR countries. Nineteen studies were identified as suitable for qualitative synthesis, and three as suitable for meta-analysis. Most women had a positive intention to have an HPV vaccine (range 57%-85%). Having a positive intention to vaccinate was significantly higher among women not aware of HPV infection (OR: 1.34, 95% CI: 1.02-1.76) and HPV vaccine (OR: 1.57, 95% CI: 1.26-1.96). Lower knowledge level and less confidence in safety and efficacy of the vaccine, negatively affected intention to vaccinate. Perceiving the vaccine to be expensive, low perception of contracting HPV infection and cervical cancer, and lack of concrete recommendations from healthcare providers also negatively affected intention to vaccinate. This review suggests the decision-making processes of women in SEAR and WPR is influenced by the cost of vaccination, perceived efficacy and safety of vaccine, provision of information on vaccination, and the awareness about HPV infection and the HPV vaccine.

PMID:
29483541
PMCID:
PMC5832144
DOI:
10.1038/s41598-018-21912-x
[Indexed for MEDLINE]
Free PMC Article

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