Whole-exome sequencing of a meningeal melanocytic tumour reveals activating CYSLTR2 and EIF1AX hotspot mutations and similarities to uveal melanoma

Brain Tumor Pathol. 2018 Apr;35(2):127-130. doi: 10.1007/s10014-018-0308-1. Epub 2018 Feb 23.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged, 80 and over
  • DNA Methylation
  • Diagnosis, Differential
  • Eukaryotic Initiation Factor-1 / genetics*
  • Exome Sequencing*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Melanoma / diagnosis
  • Melanoma / genetics*
  • Melanoma / pathology
  • Melanoma / surgery
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / genetics*
  • Meningeal Neoplasms / pathology
  • Mutation*
  • Receptors, Leukotriene / genetics*
  • Uveal Neoplasms

Substances

  • Eukaryotic Initiation Factor-1
  • Receptors, Leukotriene
  • eukaryotic peptide initiation factor-1A
  • cysteinyl leukotriene receptor 2

Supplementary concepts

  • Uveal melanoma