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Nutrients. 2018 Feb 16;10(2). pii: E221. doi: 10.3390/nu10020221.

The Effect of Whey Protein Supplementation on the Temporal Recovery of Muscle Function Following Resistance Training: A Systematic Review and Meta-Analysis.

Author information

1
Human Science Research Unit, Centre for Interventions in Infection, Inflammation & Immunity (4i), University of Limerick, Limerick V94 T9PX, Ireland. robert.davies@ul.ie.
2
Food, Health Ireland, Physical Education and Sport Sciences Department, University of Limerick, Limerick V94 T9PX, Ireland. robert.davies@ul.ie.
3
Human Science Research Unit, Centre for Interventions in Infection, Inflammation & Immunity (4i), University of Limerick, Limerick V94 T9PX, Ireland. brian.carson@ul.ie.
4
Food, Health Ireland, Physical Education and Sport Sciences Department, University of Limerick, Limerick V94 T9PX, Ireland. brian.carson@ul.ie.
5
Human Science Research Unit, Centre for Interventions in Infection, Inflammation & Immunity (4i), University of Limerick, Limerick V94 T9PX, Ireland. phil.jakeman@ul.ie.
6
Food, Health Ireland, Physical Education and Sport Sciences Department, University of Limerick, Limerick V94 T9PX, Ireland. phil.jakeman@ul.ie.

Abstract

Whey protein (WP) is a widely consumed nutritional supplement, known to enhance strength and muscle mass during resistance training (RT) regimens. Muscle protein anabolism is acutely elevated following RT, which is further enhanced by WP. As a result, there is reason to suggest that WP supplementation may be an effective nutritional strategy for restoring the acute loss of contractile function that occurs following strenuous RT. This systematic review and meta-analysis provides a synthesis of the literature to date, investigating the effect of WP supplementation on the recovery of contractile function in young, healthy adults. Eight studies, containing 13 randomised control trials (RCTs) were included in this review and meta-analysis, from which individual standardised effect sizes (ESs) were calculated, and a temporal overall ES was determined using a random-effects model. Whilst only half of the individual studies reported beneficial effects for WP, the high-quality evidence taken from the 13 RCTs was meta-analysed, yielding overall positive small to medium effects for WP from < 24 to 96 h (ES range = 0.4 to 0.7), for the temporal restoration of contractile function compared to the control treatment. Whilst the effects for WP were shown to be consistent over time, these results are limited to 13 RCTs, principally supporting the requirement for further comprehensive research in this area.

KEYWORDS:

athletic performance; dietary supplements; exercise; humans; recovery of function; resistance training; skeletal muscle; sports; weight lifting; whey proteins

PMID:
29462923
PMCID:
PMC5852797
DOI:
10.3390/nu10020221
[Indexed for MEDLINE]
Free PMC Article

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