Send to

Choose Destination
Skin Appendage Disord. 2018 Jan;4(1):18-24. doi: 10.1159/000477353. Epub 2017 Jul 6.

A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification.

Author information

Department of Dermatology, Universitat International Catalunya, Barcelona, Spain.


Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia. PRP is a biological product defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. It is obtained from the blood of patients collected before centrifugation. The knowledge of the biology, mechanism of action, and classification of the PRP should help clinicians better understand this new therapy and to easily sort and interpret the data available in the literature regarding PRP. In this review, we try to provide useful information for a better understanding of what should and should not be treated with PRP.


Autologous therapy; Biology; Mechanism of action; Plasma; Platelet-rich plasma

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center