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Clin Imaging. 2018 Sep - Oct;51:50-58. doi: 10.1016/j.clinimag.2018.02.002. Epub 2018 Feb 7.

Estimation of hepatic fat fraction using modified Dixon magnetic resonance imaging techniques: effect of liver cirrhosis.

Author information

1
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: 20140066@kuh.ac.kr.
2
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: heesun@kuh.ac.kr.
3
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: yjkim@kuh.ac.kr.
4
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: yumihye@gmail.com.
5
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: radsijung@kuh.ac.kr.
6
Department of Radiology, Konkuk University School of Medicine, 120-1, Neungdong-ro, Gwangjin-gu, Seoul 05030, Republic of Korea. Electronic address: haejeong@kuh.ac.kr.

Abstract

PURPOSE:

To evaluate modified Dixon MRI techniques in hepatic fat estimation and to assess the effect of cirrhosis.

METHODS:

235 patients who underwent liver MRI were included. Correlation between modified Dixon techniques with MRS was assessed. Accuracy of MR techniques in hepatic fat estimation was calculated, and the result was compared between patients with/without liver cirrhosis.

RESULTS:

Correlation between modified Dixon and MRS was better in group without liver cirrhosis, and accuracy of modified Dixon method was higher in group without liver cirrhosis.

CONCLUSIONS:

Modified Dixon techniques estimate hepatic fat fraction noninvasively, but the result can be influenced by the presence of liver cirrhosis.

KEYWORDS:

Cirrhosis; Hepatic steatosis; Magnetic resonance imaging; Magnetic resonance spectroscopy; Multi-echo Dixon

PMID:
29448119
DOI:
10.1016/j.clinimag.2018.02.002
[Indexed for MEDLINE]

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