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Int J Pediatr Otorhinolaryngol. 2018 Mar;106:1-9. doi: 10.1016/j.ijporl.2017.12.027. Epub 2017 Dec 30.

Risk of childhood otitis media with focus on potentially modifiable factors: A Danish follow-up cohort study.

Author information

1
Department of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Denmark. Electronic address: asbp@regionsjaelland.dk.
2
Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Department of Infectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
3
Research Unit of General Practice Institute of Public Health, University of Southern Denmark, Denmark.
4
Department of Epidemiology Research, Centre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
5
Department of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Denmark.

Abstract

INTRODUCTION:

Otitis media is the primary cause of antibiotic prescription in children. Two-thirds of all children experience at least one episode of otitis media before the age of 7 years. The aim of this study was to characterise the attributable effect of several modifiable risk exposures on the risk of >3 episodes of otitis media at age 18 months and 7 years within a large prospective national birth cohort.

METHODS:

The study used the Danish National Birth Cohort comprising information about otitis media and risk exposures from more than 50,000 mother-child pairs from the period 1996-2002. Logistic regression models were used to estimate odds ratios for the risk factors and to calculate the population attributable fraction.

RESULTS:

Short time with breastfeeding, early introduction to daycare, cesarean section, and low compliance to the national vaccination program were all associated with an increased risk of >3 episodes of otitis media at 18 months of age and at 7 years of age. The fraction of children with otitis media attributed from breastfeeding lasting for less than 6 months was 10%. Introduction to daycare before the age of 12 months attributed with 20% of the cases of >3 episodes of otitis media.

CONCLUSIONS:

Short duration of breastfeeding, early introduction into daycare, cesarean section, and low compliance with the national vaccination program increased the risk of experiencing >3 episodes of otitis media at 18 months, and at 7 years of age. These are factors that all can be modulated.

KEYWORDS:

Cohort studies; Epidemiology; Infections; Otitis media; Pediatric; Public health

PMID:
29447878
DOI:
10.1016/j.ijporl.2017.12.027
[Indexed for MEDLINE]

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