18F-FDG avid Sclerosing Angiomatoid Nodular Transformation (SANT) of spleen on PET-CT - a rare mimicker of metastasis

Nucl Med Rev Cent East Eur. 2018;21(1):53. doi: 10.5603/NMR.2018.0014.

Abstract

Sclerosing Angiomatoid Nodular Transformation (SANT) is a rare benign vascular tumor of spleen. It consists of multiple angiomatoid nodules surrounded by dense fibrous tissue that often coalesces centrally to form a scar, which is considered to be a characteristic feature. These are usually asymptomatic and incidentally detected on imaging for other underlying pathology. SANTs can be 18F-Fluorodeoxyglucose (18F-FDG) avid on positron emission tomography-computed tomography (PET-CT) and thus can lead to false positive finding in oncological patients.

Keywords: 18FDG; PET-CT; Sclerosing Angiomatoid Nodular Transformation; Spleen.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18*
  • Histiocytoma, Benign Fibrous / diagnostic imaging*
  • Humans
  • Middle Aged
  • Neoplasm Metastasis
  • Positron Emission Tomography Computed Tomography*
  • Spleen / diagnostic imaging*

Substances

  • Fluorodeoxyglucose F18