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Ann Pediatr Cardiol. 2018 Jan-Apr;11(1):100-102. doi: 10.4103/apc.APC_130_17.

Acquired ventricular septal defect due to infective endocarditis.

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Department of Pediatrics, Division of Pediatric Cardiology, The University of Iowa Stead Family Children's Hospital, lowa, USA.


Acquired intracardiac left-to-right shunts are rare occurrences. Chest trauma and myocardial infection are well-known causes of acquired ventricular septal defect (VSD). There have been several case reports describing left ventricle to right atrium shunt after infective endocarditis (IE). We present here a patient found to have an acquired VSD secondary to IE of the aortic and tricuspid valves in the setting of a known bicuspid aortic valve. This is the first case reported of acquired VSD in a pediatric patient in the setting of IE along with literature review of acquired left-to-right shunts.


Endocarditis; infective endocarditis; ventricular septal defect

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