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BMJ Case Rep. 2018 Feb 8;2018. pii: bcr-2017-222937. doi: 10.1136/bcr-2017-222937.

Reversible bioprosthetic valve thrombosis from eosinophilia.

Author information

1
Department of Cardiology, Cardio-Thoracic Sciences Centre, All India Institute of Medical Sciences, New Delhi, India.

Abstract

A 31-year-old man with a mitral bioprosthetic valve presented with recent worsening of exertional dyspnoea 7 years after the mitral valve replacement. Evaluation revealed an increased gradient across the thickened mitral bioprosthetic valve leaflets. Marked eosinophilia was present and was considered as a putative cause for bioprosthetic valve thrombosis. The treatment with systemic corticosteroids and oral anticoagulation led to complete resolution of symptoms with significant decrease in mitral bioprosthetic valve gradient and leaflet thinning. The case is reported to highlight the fact that eosinophilia may cause reversible bioprosthetic valve thrombosis.

KEYWORDS:

cardiovascular medicine; valvar diseases

PMID:
29437808
DOI:
10.1136/bcr-2017-222937
[Indexed for MEDLINE]

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