Format

Send to

Choose Destination
Sci Data. 2018 Feb 13;5:180009. doi: 10.1038/sdata.2018.9.

The Brain/MINDS 3D digital marmoset brain atlas.

Author information

1
Neuroinformatics Japan Center, RIKEN Brain Science Institute, Wako-shi, Saitama 351-0198, Japan.
2
Laboratory for Symbolic Cognitive Development, RIKEN Brain Science Institute, Wako-shi, Saitama 351-0198, Japan.
3
Laboratory for Marmoset Neural Architecture, RIKEN Brain Science Institute, Wako-shi, Saitama 351-0198, Japan.
4
Animal Resources Section, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami, Okinawa 904-0495, Japan.

Abstract

We present a new 3D digital brain atlas of the non-human primate, common marmoset monkey (Callithrix jacchus), with MRI and coregistered Nissl histology data. To the best of our knowledge this is the first comprehensive digital 3D brain atlas of the common marmoset having normalized multi-modal data, cortical and sub-cortical segmentation, and in a common file format (NIfTI). The atlas can be registered to new data, is useful for connectomics, functional studies, simulation and as a reference. The atlas was based on previously published work but we provide several critical improvements to make this release valuable for researchers. Nissl histology images were processed to remove illumination and shape artifacts and then normalized to the MRI data. Brain region segmentation is provided for both hemispheres. The data is in the NIfTI format making it easy to integrate into neuroscience pipelines, whereas the previous atlas was in an inaccessible file format. We also provide cortical, mid-cortical and white matter boundary segmentations useful for visualization and analysis.

PMID:
29437168
PMCID:
PMC5810420
DOI:
10.1038/sdata.2018.9
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center