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Ann Intensive Care. 2018 Feb 9;8(1):22. doi: 10.1186/s13613-018-0369-7.

Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes.

Author information

1
Division of Nephrology and Renal Transplantation, Department of Medicine, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035, Lisbon, Portugal. joana.estrelagameiro@gmail.com.
2
Division of Nephrology and Renal Transplantation, Department of Medicine, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035, Lisbon, Portugal.

Abstract

Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies using modern standardized classifications for AKI reported a variable incidence of AKI after major abdominal surgery ranging from 3 to 35%. Several patient-related, procedure-related factors and postoperative complications were identified as risk factors for AKI in this setting. AKI following major abdominal surgery has been shown to be associated with poor short- and long-term outcomes. Herein, we provide a contemporary and critical review of AKI after major abdominal surgery focusing on its incidence, risk factors, pathogeny and outcomes.

KEYWORDS:

Acute kidney injury; Incidence; Pathogenesis; Postoperative; Prognosis; Risk factors

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