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Cell. 2018 Feb 8;172(4):638-640. doi: 10.1016/j.cell.2018.01.024.

Building a Stable Relationship: Ensuring Homeostasis among Cell Types within a Tissue.

Author information

1
Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, Center for Systems and Synthetic Biology, University of California, San Francisco, CA 94158, USA.
2
Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, Center for Systems and Synthetic Biology, University of California, San Francisco, CA 94158, USA. Electronic address: wendell.lim@ucsf.edu.

Abstract

Many processes controlling cell growth and death are well characterized for individual cell lineages, but how ensembles of different cell types in a tissue regulate collective size and composition remains unclear. In this issue of Cell, Zhou et al. employ experiments and theory to uncover design principles of tissue homeostasis arising from cross-talk between fibroblasts and macrophages.

PMID:
29425483
DOI:
10.1016/j.cell.2018.01.024
[Indexed for MEDLINE]
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