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Echocardiography. 2018 Apr;35(4):559-562. doi: 10.1111/echo.13824. Epub 2018 Feb 8.

Acute myocardial infarction complicated with ventricular septal rupture and intracranial hemorrhage.

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Cardiology Department, University of Health Sciences, Kartal Kosuyolu Education and Research Hospital, Istanbul, Turkey.


Ventricular septal rupture (VSR) is a rare but fatal complication of acute myocardial infarction (AMI) with an associated mortality that ranges from 41% to 80%. The treatment consists of supplemental oxygenation, afterload reduction, intraaortic balloon pump, and surgical repair. In selected patients, extracorporeal membrane oxygenation (ECMO) and/or percutaneous closure of the defect can be considered if anatomically appropriate. Echocardiography evaluates the morphology and location of the defect, anatomical concerns for percutaneous closure, and accompanying pathologies. We present a 48-year-old man with inferior myocardial infarction and basal VSR who was not a candidate for percutaneous closure. Surgery was planned, but he died from extensive subarachnoid and intracranial hemorrhage.


acute myocardial infarction; ventricular septal rupture

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