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Gastroenterol Clin North Am. 2018 Mar;47(1):107-137. doi: 10.1016/j.gtc.2017.10.003.

The Role of Diet in the Treatment of Irritable Bowel Syndrome: A Systematic Review.

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Department of Internal Medicine, Sinai Hospital of Baltimore, 2421 Cylburn Avenue, Baltimore, MD 21215, USA.
Gastroenterology Department, University of Rochester Medical Center, 101 Portsmouth Terrace, Rochester, NY 14642, USA.
The Johns Hopkins University School of Medicine, Welch Medical Library, 2024 East Monument Street, Baltimore, MD 21287, USA.
Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 600 North Wolfe Street CARN 464B, Baltimore, MD 21287, USA. Electronic address:


Irritable bowel syndrome (IBS) is a multifaceted illness involving maladaptive shifts in the gut microbiota that affect the enteric nervous and immune systems, mucosal barrier function, the balance of neurotransmitters and hormones, and emotional well-being. There is abundant evidence indicating that certain foods elicit symptoms in IBS. Numerous elimination-type diets have been shown to alleviate symptoms. However, among these, the most controversial is a group of foods called fructo, oligo-, di-, and monosaccharides and polyols (FODMAPs). This paper reviews the role of diet and systematically analyze the literature for the role of FODMAPs in IBS.


Diet; Elimination diets; FODMAPs; Fiber; Food sensitivities; Gluten; Irritable bowel syndrome; Nutrition

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