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Hum Immunol. 2018 May;79(5):356-361. doi: 10.1016/j.humimm.2018.01.016. Epub 2018 Feb 19.

Mechanisms and biomarkers of immune quiescence in kidney transplantation.

Author information

1
Division of Nephrology, Faculty of Medicine, Department of Internal Medicine, Khon Kaen University, Khon Kaen, Thailand; Division of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.
2
Division of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.
3
Division of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, United States. Electronic address: minnie.sarwal@ucsf.edu.

Abstract

This review discusses the current understanding of biomarkers of immune quiescence based on reviews of published literature in kidney transplant operational tolerance and mechanistic studies based on a better characterization of the stable, well-functioning renal allograft.

KEYWORDS:

Immune tolerance; Molecular biomarkers; Regulatory T cells; Regulatory dendritic cells; Tolerant footprint

PMID:
29408630
DOI:
10.1016/j.humimm.2018.01.016
[Indexed for MEDLINE]

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