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Trends Endocrinol Metab. 2018 Mar;29(3):164-177. doi: 10.1016/j.tem.2018.01.003. Epub 2018 Feb 3.

Maternal Exercise Improves the Metabolic Health of Adult Offspring.

Author information

1
Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
2
Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Electronic address: kristin.stanford@osumc.edu.

Abstract

The intrauterine environment can modulate the course of development and confer an enduring effect on offspring health. The effects of maternal diet to impair offspring metabolic health are well established, but the effects of maternal exercise on offspring metabolic health have been less defined. Because physical exercise is a treatment for obesity and type 2 diabetes (T2D), maternal exercise is an appealing intervention to positively influence the intrauterine environment and improve the metabolic health of offspring. Recent research has provided insights into the effects of maternal exercise on the metabolic health of adult offspring, which is the focus of this review.

PMID:
29402734
PMCID:
PMC5826804
DOI:
10.1016/j.tem.2018.01.003
[Indexed for MEDLINE]
Free PMC Article

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