Format

Send to

Choose Destination
Neurophotonics. 2018 Jan;5(1):015001. doi: 10.1117/1.NPh.5.1.015001. Epub 2018 Jan 25.

Concurrent measurement of cerebral hemodynamics and electroencephalography during transcranial direct current stimulation.

Author information

1
ICFO-Institut de Ciències Fotòniques, Barcelona Institute of Science and Technology, Castelldefels, Barcelona, Spain.
2
Starlab, Barcelona, Spain.
3
Neuroelectrics Barcelona, Barcelona, Spain.
4
Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

Abstract

Transcranial direct current stimulation (tDCS) is currently being used for research and treatment of some neurological and neuropsychiatric disorders, as well as for improvement of cognitive functions. In order to better understand cerebral response to the stimulation and to redefine protocols and dosage, its effects must be monitored. To this end, we have used functional diffuse correlation spectroscopy (fDCS) and time-resolved functional near-infrared spectroscopy (TR-fNIRS) together with electroencephalography (EEG) during and after stimulation of the frontal cortex. Twenty subjects participated in two sessions of stimulation with two different polarity montages and twelve also underwent a sham session. Cerebral blood flow and oxyhemoglobin concentration increased during and after active stimulation in the region under the stimulation electrode while deoxyhemoglobin concentration decreased. The EEG spectrum displayed statistically significant power changes across different stimulation sessions in delta (2 to 4 Hz), theta (4 to 8 Hz), and beta (12 to 18 Hz) bands. Results suggest that fDCS and TR-fNIRS can be employed as neuromonitors of the effects of transcranial electrical stimulation and can be used together with EEG.

KEYWORDS:

diffuse correlation spectroscopy; time-resolved near-infrared spectroscopy; transcranial direct current stimulation

Supplemental Content

Full text links

Icon for Society of Photo-Optical Instrumentation Engineers Icon for PubMed Central
Loading ...
Support Center