Format

Send to

Choose Destination
Pain. 2018 Mar;159(3):603-609. doi: 10.1097/j.pain.0000000000001141.

Itch and neuropathic itch.

Author information

1
Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
2
Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, PA, USA.

Abstract

Neuropathic itch is a pathological condition that is due to damage within the nervous system. This type of itch can be severe and unrelenting, which has a very negative impact on quality of life. Neuropathic itch is more common than generally appreciated because most types of neuropathic pain have a neuropathic itch counterpart. Unfortunately, much like neuropathic pain, there is a lack of effective treatments for neuropathic itch. Here, we consider the neural basis of itch and then describe how injuries within these neural circuits can lead to neuropathic itch in both animal models and human disease states.

PMID:
29389746
PMCID:
PMC6106783
[Available on 2019-03-01]
DOI:
10.1097/j.pain.0000000000001141

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center