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Chem Commun (Camb). 2018 Feb 15;54(15):1869-1872. doi: 10.1039/c7cc09518j.

Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action.

Author information

1
School of Molecular Sciences, University of Western Australia, Crawley, WA 6009, Australia. keith.stubbs@uwa.edu.au joshua.mylne@uwa.edu.au.

Abstract

Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.

PMID:
29388638
DOI:
10.1039/c7cc09518j
[Indexed for MEDLINE]

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