Format

Send to

Choose Destination
Medicine (Baltimore). 2017 Dec;96(52):e9467. doi: 10.1097/MD.0000000000009467.

Recurrent Kaposi sarcoma associated with Koebner phenomenon in two HIV-seronegative patients: Two case reports and a review of the literature.

Author information

1
Department of Clinical and Experimental Oncology, Veneto Institute of Oncology, IOV IRCCS.
2
Department of Cardiac, Thoracic and Vascular Sciences, Section of Pathology.
3
Department of Neurosciences, Otolaryngology Section, University of Padua.
4
Immunology and Molecular Oncology, Veneto Institute of Oncology, IOV IRCCS.
5
Dermatology Unit, Department of Medicine, University of Padua, Padua, Italy.

Abstract

RATIONALE:

Koebner phenomenon is occasionally reported in patients affected by classic Kaposi sarcoma (KS).

PATIENT CONCERNS:

Here, we report 2 cases of KS associated with Koebner phenomenon and the correlation of human herpesvirus 8 molecular analysis with the clinical outcome.

INTERVENTIONS:

In the first case, a patient with a history of sporadic cutaneous KS developed a recurrent lesion at the laryngeal tract, the site of a previous nodulectomy. In our second case, immunodeficiency induced by chemotherapy triggered the development of KS and Koebner phenomenon was limited to the skin at the site of safenectomy.

LESSONS:

Our observations suggest that careful planning of surgical treatment is required in immunocompetent and immunocompromised patients with a medical history of KS. Moreover, mucosal sites (both respiratory and in the gastrointestinal tract) should be considered as potential sites for KS development.

PMID:
29384936
PMCID:
PMC6392972
DOI:
10.1097/MD.0000000000009467
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wolters Kluwer Icon for PubMed Central
Loading ...
Support Center