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Asia Pac J Clin Nutr. 2018;27(2):284-292. doi: 10.6133/apjcn.042017.12.

Selenium in infant formula milk.

He MJ1,2, Zhang SQ1,2, Mu W3, Huang ZW4,2.

Author information

1
Key laboratory of Trace Element Nutrition of National Health and Family Planning Commision of the People's Republic of China, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
2
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, China.
3
Department of Genetics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, North Carolina, USA.
4
Key laboratory of Trace Element Nutrition of National Health and Family Planning Commision of the People's Republic of China, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. Email: zhenwuhuang@sina.com.

Abstract

Formula-based animal milk is an alternative source of infant nutrition in many cases when breastfeeding is unacceptable or inaccessible; however, these replacements often have low selenium levels. The composition of infant formula milk should be as close as possible to that of human breast milk, both in content and chemical speciation. Selenium is an essential trace element for infants. Generally, human breast milk is the ideal food to ensure adequate infant Se intake. However, to date, sodium selenite or sodium selenate has been used as selenium supplementation in infant formula milk in most countries. This inorganic Se, which is not a natural component of food, may not be the optimal speciation for Se supplementation in infant formula milk. Advances in speciation in foods, especially in animal milk, suggest that future proposals for selenium speciation in human breast milk can lead to discussions regarding the most favorable methods of selenium supplementation in infant formula milk.

PMID:
29384312
DOI:
10.6133/apjcn.042017.12
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