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Acta Anaesthesiol Scand. 1986 Jan;30(1):7-9.

Ketanserin and malignant hyperthermia in pigs.

Abstract

Four Danish landrace pigs susceptible to MH were challenged with halothane and suxamethonium on six occasions after pretreatment with the serotonin-S2 antagonist ketanserin 0.4 mg/kg (three animals) or 4 mg/kg (three animals). The animals developed typical MH on all occasions despite the pretreatment. Dantrolene remains the only specific drug for prevention and treatment of MH.

PMID:
2938396
[PubMed - indexed for MEDLINE]
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