An Unusual Cluster of Neuroinvasive Lyme Disease Cases Presenting With Bannwarth Syndrome in the Midwest United States

Aditya Shah; John C O'Horo; John W Wilson; Dane Granger; Elitza S Theel

doi:10.1093/ofid/ofx276

An Unusual Cluster of Neuroinvasive Lyme Disease Cases Presenting With Bannwarth Syndrome in the Midwest United States

Open Forum Infect Dis. 2017 Dec 23;5(1):ofx276. doi: 10.1093/ofid/ofx276. eCollection 2018 Jan.

Authors

Aditya Shah¹, John C O'Horo^{1

2}, John W Wilson¹, Dane Granger³, Elitza S Theel³

Affiliations

¹ Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota.
² Division of Pulmonary and Critical Care, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
³ Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

Abstract

Bannwarth syndrome (BWS), an infrequent manifestation of neuroinvasive Lyme disease (LD) characterized by radiculopathy, neuropathy, and lymphocytic pleocytosis, is more commonly documented in Europe than North America. Here, we describe a cluster of 5 neuroinvasive LD cases with BWS in the upper Midwest United States between July and August 2017.

Keywords: Bannwarth syndrome; Garin-Bujadoux-Bannwarth syndrome; Lyme disease; neuroborreliosis; neuroinvasive.