Format

Send to

Choose Destination
BMJ Case Rep. 2018 Jan 26;2018. pii: bcr-2017-221435. doi: 10.1136/bcr-2017-221435.

Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency.

Author information

1
Department of Psychiatry and Human Behavior, UC Irvine Medical Center, Orange, California, USA.
2
Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
3
F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
4
Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
5
Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
6
David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
7
UCLA Fielding School of Public Health, Los Angeles, California, USA.

Abstract

Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed Cryptococcus neoformans meningitis. An investigation of cannabis samples from the patient's preferred dispensary demonstrated contamination with several varieties of Cryptococcus, including C. neoformans, and other opportunistic fungi. These findings raise concern regarding the safety of dispensary-grade cannabis, even in immunocompetent users.

KEYWORDS:

disease and health outcomes; drugs misuse (including addiction); exposures; healthcare improvement and patient safety; infectious diseases

PMID:
29374632
DOI:
10.1136/bcr-2017-221435
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center