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J Clin Gastroenterol. 2018 Nov/Dec;52(10):880-884. doi: 10.1097/MCG.0000000000000991.

Comparative Assessment of Patient Preferences and Tolerability in Barrett Esophagus Screening: Results From a Randomized Trial.

Author information

1
Divisions of Gastroenterology and Hepatology.
2
Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
3
Healthcare Policy and Research, Mayo Clinic.

Abstract

GOALS:

To determine patient preference for the Barrett esophagus (BE) screening techniques.

BACKGROUND:

Sedated esophagogastroduodenoscopy (sEGD) and unsedated transnasal endoscopy (uTNE) are both potential techniques for BE screening. However, systematic assessment of patient preference for these 2 techniques is lacking. As part of a comparative effectiveness randomized trial of BE screening modalities, we measured short-term patient preferences for the following approaches: in-clinic uTNE (huTNE), mobile-based uTNE (muTNE), and sEGD using a novel assessment instrument.

STUDY:

Consenting community patients without known BE were randomly assigned to receive huTNE, muTNE, or sEGD, followed by a telephone administered preference and tolerability assessment instrument 24 hours after study procedures. Patient preference was measured by the waiting trade-off method.

RESULTS:

In total, 201 patients completed screening with huTNE (n=71), muTNE (n=71), or sEGD (n=59), and a telephone interview. Patients' preferences for sEGD and uTNE using the waiting trade-off method were comparable (P=0.51). Although tolerability scores were superior for sEGD (P<0.001) compared with uTNE, scores for uTNE examinations were acceptable.

CONCLUSIONS:

Patient preference is comparable between sEGD and uTNE for diagnostic examinations conducted in an endoscopy suite or in a mobile setting. Given acceptable tolerability, uTNE may be a viable alternative to sEGD for BE screening.

PMID:
29369237
PMCID:
PMC6056346
[Available on 2019-11-01]
DOI:
10.1097/MCG.0000000000000991

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