Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

Pharm Res. 2018 Jan 8;35(2):26. doi: 10.1007/s11095-017-2336-7.
No abstract available

Keywords: antibiotics; epithelial lining fluid; lung; pharmacokinetics; prediction.

Publication types

  • Validation Study

MeSH terms

  • Anti-Bacterial Agents / pharmacokinetics*
  • Anti-Bacterial Agents / therapeutic use
  • Area Under Curve
  • Bronchoalveolar Lavage Fluid / chemistry
  • Humans
  • Lung / metabolism*
  • Models, Biological*
  • Permeability
  • Pneumonia / drug therapy
  • Predictive Value of Tests
  • Respiratory Mucosa / metabolism*
  • Tissue Distribution

Substances

  • Anti-Bacterial Agents