Alcohol use disorder and cognitive impairment in old age patients: A 6 months follow-up study in an outpatient unit in Barcelona

Psychiatry Res. 2018 Mar:261:361-366. doi: 10.1016/j.psychres.2017.12.069. Epub 2018 Jan 4.

Abstract

There has been little research about deleterious effects, including cognitive impairment, related to hazardous long-term alcohol use in old adults. This study aims to assess cognitive decline in old patients with alcohol use disorder and changes in cognitive state at 6 months follow-up, achieving or not abstinence. A six-month follow-up study was conducted in an outpatient center in Barcelona on a sample of old adults (≥65 years old) who had hazardous alcohol use. The sample was compared with healthy volunteers adjusted for age, sex and years of education. A neuropsychological protocol was performed at baseline and after 6 months follow-up covering four cognitive domains: attention, visuospatial abilities, memory and executive functions. Several domains were significant impaired at baseline: visual immediate and delayed recall, working memory, immediate verbal learning, total words learned, set switching and sustained attention. At 6 months reassessment, alcohol abstinence was achieved in 93.5% of patients and it was detected a trend towards improvement in direct mean scores of all cognitive areas, although it was not significant. The current study points out a cognitive impairment in many areas secondary to alcohol long-term hazardous use in old adults. A trend towards cognitive improvement after recovery was detected in most patients.

Keywords: Alcohol use; Cognitive impairment; Executive functions; Neuropsychology; Old adults.

MeSH terms

  • Aged
  • Alcohol Abstinence / psychology
  • Alcoholism / psychology*
  • Attention
  • Cognitive Dysfunction / etiology*
  • Executive Function
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Memory, Short-Term
  • Outpatients / psychology
  • Spain
  • Time Factors
  • Verbal Learning