(A) Venn diagram of m6A tagged-transcripts identified by m6A-CLIP-SMART-seq in adult mouse DRGs under naïve and SNL D1 conditions.
(B) Dynamic changes of m6A sites in transcripts from adult DRGs at SNL D1. Cn8ghanges of m6A sites are plotted for the whole transcript (total) and in different sub-transcript regions (5′ UTR, CDS, and 3′ UTR). CDS: coding sequence region.
(C) m6A-CLIP-SMART-seq examples for multiple RAGs. Shown are sample tracks for both m6A-CLIP-seq (top panels) and RNA-seq (bottom panels). CLIP unique tag coverage is shown in black, and m6A sites are indicated with vertical lines.
(D) Comparison of dynamic m6A sites between RAGs and non-RAGs, and between transcripts encoding ribosomal subunit-related and non-ribosomal subunit-related proteins, in different transcript regions (total, 5′ UTR, CDS, and 3′ UTR) under naïve and SNL D1 conditions. Values represent mean differential m6A tag numbers (n = 154 RAGs and 5,867 non RAGs; n = 55 ribosomal subunit-related and 5,966 non-ribosomal subunit-related genes; ***P < 0.001; one-way ANOVA with Tukey’s post hoc test).
(E) GO enrichment analyses of transcripts with differential m6A sites at SNL D1.
See also .