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Ophthalmic Plast Reconstr Surg. 2018 May/Jun;34(3):e72-e73. doi: 10.1097/IOP.0000000000001045.

A Common Procedure With an Uncommon Pathology: Triamcinolone Acetonide Eyelid Injection.

Author information

1
Department of Ophthalmology, David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
2
Harvard Medical School.
3
Ophthalmic Consultants of Boston, Boston, Massachusetts, U.S.A.

Abstract

Local corticosteroid injections are frequently employed by ophthalmologists to treat a variety of ocular, periocular, and orbital inflammatory conditions. Triamcinolone acetonide is a slowly dissolving crystalline corticosteroid that is often used for this purpose because of its prolonged anti-inflammatory effect. On occasion, previously injected corticosteroid material persists in tissues longer than anticipated, creating nodules that may masquerade as other disease conditions, or appearing incidentally in excised lesions on histopathologic examination. The histopathologic features of corticosteroid residues are unfamiliar to most ophthalmic pathologists and general pathologists. These features are described herein. Triamcinolone acetonide deposits in the skin appear as pale eosinophilic lakes of acellular frothy material on hematoxylin-eosin staining and are occasionally surrounded by a mild inflammatory reaction.

PMID:
29346171
DOI:
10.1097/IOP.0000000000001045
[Indexed for MEDLINE]

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