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Exerc Sport Sci Rev. 2018 Apr;46(2):97-104. doi: 10.1249/JES.0000000000000143.

The Nuclear Receptor Nor-1 Is a Pleiotropic Regulator of Exercise-Induced Adaptations.

Author information

1
Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Queensland.

Abstract

Exercise induces various physical and metabolic changes in skeletal muscle that adaptively reprograms this tissue to current physiological and environmental demands. Underlying these changes are broad modifications to gene expression. We postulate that the nuclear hormone receptor, Nor-1, is activated after exercise, and this transcription factor modifies gene expression to drive the molecular and cellular adaptations associated with contractile reorganization.

PMID:
29346164
DOI:
10.1249/JES.0000000000000143
[Indexed for MEDLINE]

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