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Immunity. 2018 Jan 16;48(1):9-11. doi: 10.1016/j.immuni.2018.01.001.

New Job for NK Cells: Architects of the Tumor Microenvironment.

Author information

1
School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
2
School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland; Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA. Electronic address: llynch@bwh.harvard.edu.

Abstract

NK cells control tumor growth directly through targeted cytotoxic granule release or cytokine secretion and indirectly by orchestrating anti-tumor immune responses. In this issue of Immunity, Glasner et al. (2018) now reveal a new role for NK cells in preventing metastatic spread through controlling tumor architecture.

PMID:
29343443
DOI:
10.1016/j.immuni.2018.01.001
[Indexed for MEDLINE]
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