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Bone Marrow Transplant. 2018 May;53(5):584-590. doi: 10.1038/s41409-017-0070-8. Epub 2018 Jan 15.

A prospective, randomized evaluation of the feasibility of exergaming on patients undergoing hematopoietic stem cell transplantation.

Author information

1
Medizinische Klinik III, Klinik für Hämatologie, Onkologie und Palliativmedizin, Universitätsmedizin Rostock, Rostock, Germany.
2
Institut für Medizinische Psychologie und Medizinische Soziologie, Universitätsmedizin Rostock, Rostock, Germany.
3
Institute for Biostatistics and Informatics in Medicine and Ageing Research, Universitätsmedizin Rostock, Rostock, Germany.
4
Medizinische Klinik III, Klinik für Hämatologie, Onkologie und Palliativmedizin, Universitätsmedizin Rostock, Rostock, Germany. inken.hilgendorf@med.uni-jena.de.
5
Klinik für Innere Medizin II, Abteilung für Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Jena, Germany. inken.hilgendorf@med.uni-jena.de.

Abstract

The positive effects of physical and sports therapy for strain dependent physical practice and improved quality of life (QoL) are well known. Nevertheless, the available capacities and problem-oriented therapies in the setting of hematopoietic stem cell transplantation (HSCT) are limited. We conducted a prospective, randomized study among 42 HSCT recipients in order to investigate the influence of exergaming on Nintendo Wii® or classical physiotherapy (PT) on physical fitness and psychological well-being. The trial included evaluation of muscle strength, endurance, physical activity, distress, QoL, anxiety, and depression. Within the first 2 weeks after HSCT endurance, muscle strength and physical well-being decreased, while the value of distress increased significantly in both groups. However, exergaming on Nintendo Wii® resulted in a decrease of anxiety and depression and improved emotional well-being, while the PT group showed a contrariwise pattern of these features. Analysis of the FACT-BMT revealed a decline of QoL domains 2 and 4 weeks after HSCT and an improvement afterwards. The decrease of functional status after HSCT was accompanied by a drop of QoL and an increase of distress in both groups. However, our prospective study demonstrates that exergaming using the Nintendo Wii® is feasible and well tolerated in HSCT recipients.

PMID:
29335629
DOI:
10.1038/s41409-017-0070-8
[Indexed for MEDLINE]

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