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Org Biomol Chem. 2018 Feb 7;16(6):919-923. doi: 10.1039/c7ob02906c.

Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores.

Author information

1
Bioimaging Center, University of Geneva, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland.

Abstract

Twelve cationic helicenes and one triangulene were tested for the specific labeling of mitochondria from algal cells. Octyl ester derivative 5 readily penetrates algal cells and gives rise to clear fluorescence patterns when it is used at concentrations in the μM range. Under these conditions, cell structures are well preserved and cell survival is not compromised. Cationic helicene compounds such as 5 provide new useful tools for examining the mitochondrial network and its dynamics including fission and fusion events.

PMID:
29334105
DOI:
10.1039/c7ob02906c

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