Univariate predictors of 2-year melanoma brain metastases-free survival of patients with eventual stage IV disease. A: patient sex – female 81.7%, male 73.5% (p<0.01); B: primary location – ocular 91.5%, mucosal 87.2%, extremity 82.8%, and axial 72.3% (p<0.01); C: ulceration – yes 69.0%, no 79.8% (p<0.01); D: histologic subtype – lentigo maligna 89.9%, other 83.7%, superficial spreading 76.9%, nodular 72.1%, and desmoplastic 57.8% (p<0.01)