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BMC Res Notes. 2018 Jan 12;11(1):23. doi: 10.1186/s13104-018-3130-2.

Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder?

Author information

1
Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. nagata@medicalheart-shizu.jp.
2
Cognitive Behavioral Therapy Center, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
3
Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
4
Organization for Promotion of Tenure Truck, University of Miyazaki, 1-1, Gakuenkibanadai-Nishi, Miyazaki, 889-2192, Japan.
5
Inada Clinic, Osaka, 2-6-5 Johoku-cho, Takatsuki, Osaka, 569-0071, Japan.
6
Clinic Adachi, Gifu, 62 Oikecho, Gifu, Gifu, 500-8373, Japan.
7
United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
8
Department Psychiatry, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
9
Research Centre for Child Mental Development, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.

Abstract

OBJECTIVE:

Mental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group.

RESULTS:

Patients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment. Patients completed the Mental Defeat Scale and the Cognitive Flexibility Scale before the intervention, following eight CBT sessions, and following 16 CBT sessions, while the control group did so only prior to receiving CBT (baseline). The patients' pre-CBT Mental Defeat and Cognitive Flexibility Scale scores were significantly higher on the Mental Defeat Scale and lower on the Cognitive Flexibility Scale than those of the control group participants were. In addition, the average Mental Defeat Scale scores of the patients decreased significantly, from 22.2 to 12.4, while their average Cognitive Flexibility Scale scores increased significantly, from 42.8 to 49.5. These results suggest that CBT can reduce mental defeat and increase cognitive flexibility in patients with PD Trial registration The study was registered retrospectively in the national UMIN Clinical Trials Registry on June 10, 2016 (registration ID: UMIN000022693).

KEYWORDS:

Cognitive behavioral therapy; Cognitive flexibility; Mental defeat; Panic disorder

PMID:
29329597
PMCID:
PMC5767061
DOI:
10.1186/s13104-018-3130-2
[Indexed for MEDLINE]
Free PMC Article

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